Cardiff Airport chiefs say over 55,000 passengers have used direct flights between the Welsh and Scottish capitals in the last three years.
Loganair launched its direct route to and from Edinburgh in August 2021, filling the gap left after the collapse of Flybe, shortly before the Covid pandemic began in March 2020.
Airport chiefs are marking the third anniversary of their partnership with the UK's biggest regional airline, which has pledged to further deveop the route.
Spencer Birns, Cardiff Airport's chief executive, said: "It’s been amazing to see customers enjoy the advantages of using the Loganair flights, connecting two great countries in the UK."
"These convenient flights help families and businesses stay connected. We look forward to Loganair increasing choice on the route, serving the people of Wales and Scotland through Cardiff Wales Airport."
Luke Lovegrove, CEO of Loganair, added: "It’s extremely rewarding to be celebrating this special milestone with Cardiff Wales Airport."
"We are proud to operate the only flight linking the Scottish and Welsh capitals, providing vital connectivity between two significant regional cities and supporting leisure and business travel."
"More than half of customers are travelling for leisure purposes and spend two or three days at their destination, helping to grow visitor numbers for both Scotland and Wales. We look forward to continuing to develop this important route."
Loganair operates six flights a week from Cardiff to Edinburgh Airport with journeys lasting an hour and 20 minutes each.